The experiment was conducted at Agricultural Research Station, Bangladesh Agricultural Research Institute, Daulatpur, Khulna during rabi season of 2007-08 and 2008-09. The objective of the study was to identify the suitable and profitable intercrop combination of maize with sweet potato in the coastal area. The experiment was laid out in a randomized complete block design (RCBD) with four replications. There were four treatments viz. T1: Sole maize, T2: Maize paired row + 2 rows sweet potato in between two paired rows, T3 : Maize normal row + 1 row sweet potato in between two maize rows and T4 : Sole sweet potato. Results showed that different intercropping combinations significantly influenced the yield of maize and sweet potato. The highest grain yield (8.99 t/ha) and root yield (28.75 t/ha) were recorded from sole maize and sole sweet potato respectively. But higher maize equivalent yield was obtained from T2 (12.30 t/ha). Higher LER was recorded from treatment T2 (1.27) followed by T3 (1.07) and lower LER from sole maize and sole sweet potato. Higher gross return (Tk. 184560/ha), net return (Tk. 138740/ha) and BCR (4.03) were obtained from T2 and lower gross return (Tk. 134850 /ha) net return (Tk. 93330/ha) and BCR (3.25) were obtained from T1.